ENHANCED CATALYTIC EFFECT OF FREEZE-DRIED POTASSIUM FLUORIDE FOR ALKYLATION OF PROTIC COMPOUNDS

Article abstract of DOI:10.1246/cl.1980.1089

Freeze-dried potassium fluoride was found to be much more effective as a hydrogen-bond forming catalytic reagent for alkylation of protic compounds than usual calcine-dried potassim fluoride.Phenol, thiophenol, aniline, and acetylacetone were easily alkylated with methyl or ethyl iodide in the presence of the reagent.Freeze-dried potassium fluoride, however, had no effect for the fluorination of activated chlorine compounds.