A convenient high-yield procedure for the β-hydroxyethylation of acetylenes with epoxyethane in liquid ammonia

Article abstract of DOI:10.1080/00397919108020817

3-Butyn-1-ol and homologues, RC≡CCH₂CH₂OH (R = H or alkyl), have been obtained in excellent yields from alkynyllithium derivatives, RC≡CLi, and epoxyethane in liquid ammonia.

Full text of DOI:10.1080/00397919108020817

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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A Convenient High-Yield
Procedure for the β-
Hydroxyethylation of
Acetylenes with Epoxyethane
in Liquid Ammonia
H. D. Verkruijsse a & L. Brandsma a
a Department of Preparative Organic Chemistry of ,
the University, Debye Institute Padualaan , 8, 3584,
CH, Utrecht, The Netherlands
Published online: 23 Sep 2006.
To cite this article: H. D. Verkruijsse & L. Brandsma (1991) A Convenient High-
Yield Procedure for the β-Hydroxyethylation of Acetylenes with Epoxyethane
in Liquid Ammonia, Synthetic Communications: An International Journal for
Rapid Communication of Synthetic Organic Chemistry, 21:2, 235-237, DOI:
10.1080/00397919108020817
To link to this article: http://dx.doi.org/10.1080/00397919108020817
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