Unusual reactivity of zinc borohydride - Reduction of amides to amines

Article abstract of DOI:10.1080/00397919708006038

Zinc borohydride reduces secondary amides to the corresponding N-ethyl amines in excellent yields. The reduction requires only stoichiometric quantities of hydride and does not require the addition of any Lewis acid. The amides are isolated by simple hydrolysis of the reaction mixture.

Full text of DOI:10.1080/00397919708006038

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Synthetic Communications:
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Unusual Reactivity of Zinc
Borohydride - Reduction of
Amides to Amines
a
a
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S. Narasimhan , S. Madhavan , R. Balakumar
a
&
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S. Swarnalakshmi
Centre for Agrochemical Research, SPIC
Science Foundation, Guindy, Madras, 600 032
Version of record first published: 22 Aug 2006.
To cite this article: S. Narasimhan , S. Madhavan , R. Balakumar & S.
Swarnalakshmi (1997): Unusual Reactivity of Zinc Borohydride - Reduction of
Amides to Amines, Synthetic Communications: An International Journal for Rapid
Communication of Synthetic Organic Chemistry, 27:3, 391-394
To link to this article: http://dx.doi.org/10.1080/00397919708006038
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