RSC Advances p. 30428 - 30431 (2019)
Update date:2022-08-11
Topics:
Ambala, Srinivas
Singh, Rohit
Singh, Maninder
Cham, Pankaj Singh
Gupta, Ria
Munagala, Gurunadham
Yempalla, Kushalava Reddy
Vishwakarma, Ram A.
Singh, Parvinder Pal
Here, we have developed a simple, room temperature method for the nitration of olefins by using inexpensive sodium nitrite as a source of nitro groups in the presence of trifluoroacetic acid (TFA) and potassium persulfate (K2S2O8) under an open atmosphere. Styrenes and mono-substituted olefins give stereo-selective corresponding E-nitroolefins under optimized conditions, however, 1,1-bisubstituted olefins give a mixture of E- and Z-nitroolefins. The optimized conditions work well with electron-donating, electron-withdrawing, un-substituted and heterocyclic styrenes and mono-substituted olefins and give corresponding nitroolefins with good to excellent yields.
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