Solid phase synthesis of aryl amines

Article abstract of DOI:10.1016/0040-4039(96)01633-4

A method for the solid phase synthesis of aryl amines is reported. The method involves a palladium mediated coupling reaction between aryl bromides and amines. The products are isolated in high purity and good yields. This method should prove to be a useful tool for constructing combinatorial libraries containing the aryl amine moiety.