Tetrahedron Letters p. 3763 - 3766 (1994)
Update date:2022-08-11
Topics:
Stevens, Christian V.
De Kimpe, Norbert G.
Katritzky, Alan R.
The construction of a cycloalkyl ring at the α-position of aldehydes by cyclization of ω-haloaldimines is described. Alkylation of the corresponding aldimines with α,ω-dihaloalkanes followed by treatment with LDA results in a convenient access to α,α-cycl
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