Selective 1,4-Reduction of Conjugated Aldehydes and Ketones in the Presence of Unconjugated Aldehydes and Ketones with Sodium Dithionite

Article abstract of DOI:10.1016/0040-4039(94)02406-2

Chemoselective 1,4-reduction of α,β-unsaturated aldehydes or ketones has been achieved with sodium dithionite in H2O/dioxane at 50 deg C in the presence of unsaturated (nonconjugated) and saturated aldehydes or ketones.