Synthetic Communications p. 1545 - 1550 (2007)
Update date:2022-08-11
Topics:
Manjula, Krishnappa
Pasha, Mohamed Afzal
A rapid and facile method for the conversion of primary amides to nitriles using inexpensive and readily available ZnCl2 in aqueous acetonitrile and their regeneration using ZnCl2-H2O-THF in the presence of acetamide under microwave irradiation in good yields is reported. The reactions go to completion within a minute. Copyright Taylor & Francis Group, LLC.
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