Kinetic resolution strategies II: Enhanced enantiomeric excesses and yields for the faster reacting enantiomer in lipase mediated kinetic resolutions

DOI: 10.1016/S0957-4166(00)80119-6

Source and publish data:

Tetrahedron Asymmetry p. 813 - 822 (1993)

Update date:2022-08-16

Topics:

Authors:

Brown Brown

Davies Davies

De Sousa

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Article abstract of DOI:10.1016/S0957-4166(00)80119-6

A strategy for the preparation of the faster reacting (R)-enantiomer of 1-(4-methoxyphenyl)ethanol with 95% ee in 37% overall yield via a double kinetic resolution strategy involving Pseudomonas fluorescens lipase mediated sequential acetylation and hydrolysis is described.

Full text of DOI:10.1016/S0957-4166(00)80119-6

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