Studies on DNA cleaving agents: Synthesis and chemically induced cycloaromatization of a monocyclic neocarzinostatin chromophore analogue

Article abstract of DOI:10.1016/S0040-4039(00)93481-6

The synthesis of an acyclic analogue of neocarzinostatin chromophore is described. This analogue is found to undergo cycloaromatization in the presence of thiols; the process involves a previously undetected internal hydrogen abstraction reaction.