A Quantitative Scale for the Structural Effect on Reactivity toward Nucleophilic Displacement at Silicon

Article abstract of DOI:10.1246/cl.1992.1263

The rates of solvolysis for forty different triorganochlorosilanes have been measured in 89 molpercent aqueous dioxane at 25 deg C; the logarithmic rates relative to that for trimethylchlorosilane, log k_rel = log 1R²R³SiCl)/k(Me3SiCl)>, provide a quantitative scale for the structural effect of various silyl groups on the reactivity toward nucleophilic displacement at silicon, ranging from 1.99 for HSiMe2 to -6.89 for t-BuSiPh2 groups.