Selective reduction with lithium bis- Or tris(dialkylamino)aluminum hydrides. III. Reduction of primary carboxamides to aldehydes by lithium tris(diethylamino)aluminum hydride

Article abstract of DOI:10.1016/0040-4039(91)80439-D

Both aliphatic and aromatic primary carboxamides are reduced readily to the corresponding aldehydes by lithium tris(diethylamino)aluminum hydride in THF at room temperature in yields of 50-90%.