Preparation of Alkylchromium Reagents by Reduction of Alkyl Halides with Chromium(II) Chloride under Cobalt Catalysis

Article abstract of DOI:10.1021/jo00281a004

Alkyl halides and tosylates are reduced with CrCl2 in the presence of a catalytic amount of vitamin B₁₂ or cobalt phthalocyanine to give alkylchromium reagents, which add to aldehydes without affecting the coexisting ketone or ester groups.