Tetrahedron Letters p. 6647 - 6648 (1994)
Update date:2022-08-23
Topics:
Healy, Eamonn F.
Lewis
Minniear, Amy B.
The aluminum hydride reduction of 3,4-epoxycyclopentene to 3-cyclopentenol has been previously observed1 and the complete regiospecificity of the reaction is confirmed here. A mechanism is proposed involving initial complexation of the aluminum hydride anion with the double bond followed by hydride transfer to the 3-Carbon. Analysis of the atomic charges determined from semiempirical electrostaic potentials support the proposed mechanism. Spectroscopic analysis of the resultant alcohol indicates the presence of an O-H''''''π intramolecular hydrogen bonded interaction.
View More
Chengdu Chengnuo New-Tech Co., Ltd
Contact:0086-028-85749078
Address:4 Jiuyang road,Jiulong industrial port,Chengdu, China
Chengdu CSH Pharmaceutical Co.,ltd
Contact:+86-(28)-85321971
Address:Block B,New Hope Int. Tian Fu New District, Chengdu, Sichuan, China
HANGZHOU TOYOND BIOTECH CO., LTD
Contact:+86-571-86965177
Address:No. 189, Fengqi East Road, Hangzhou, China
Guangzhou Chemical Reagent Factory
Contact:+86-20-8435 9820 or 8435 7345
Address:Southern Guangzhou, Guangdong, China
Weifang Arylchem Chemical Co., LTD
Contact:86-536-5217866
Address:Development Zone, Shouguang, Shandong Province
Doi:10.1002/anie.202000119
(2020)Doi:10.1016/j.molstruc.2013.09.041
(2014)Doi:10.1021/ol047394+
(2005)Doi:10.1016/0021-9517(69)90009-8
(1969)Doi:10.1021/np010510m
(2002)Doi:10.1080/15257770.2018.1442578
(2018)
