Reductive cleavage of tert-butyldimethylsilyl ether via intramolecular transfer of hydride

Article abstract of DOI:10.1080/00397919708004138

The cleavage of α-hydroxy tert-butyldimethylsilyl ether to diol takes place efficiently with LAH. It has been proposed that the reaction proceeds via intramolecular hydride transfer from the alkoxy aluminium hydride. In order to substantiate this, reduction of TBDMS ether with LAH in a variety of substrates was studied.

Full text of DOI:10.1080/00397919708004138

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Synthetic Communications: An
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Organic Chemistry
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Reductive Cleavage of tert-
Butyldimethylsilyl Ether via
Intramolecular Transfer of
Hydride
Parthasarathy Saravanan a , Suparna Gupta a , Arpita
DattaGupta a , Sonia Gupta a & Vinod K. Singh a
a Department of Chemistry , Indian Institute of
Technology , Kanpur, India , 208 016
Published online: 22 Aug 2006.
To cite this article: Parthasarathy Saravanan , Suparna Gupta , Arpita DattaGupta ,
Sonia Gupta & Vinod K. Singh (1997) Reductive Cleavage of tert-Butyldimethylsilyl
Ether via Intramolecular Transfer of Hydride, Synthetic Communications: An
International Journal for Rapid Communication of Synthetic Organic Chemistry, 27:15,
2695-2699, DOI: 10.1080/00397919708004138
To link to this article: http://dx.doi.org/10.1080/00397919708004138
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