A Convenient Synthesis of Enantiomerically Pure (2R,3S)- and (2S,3R)-3-Hydroxy-2-methylbutanoic Esters

DOI: 10.1055/s-1988-27629

Source and publish data:

Synthesis p. 538 - 540 (1988)

Update date:2022-08-17

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Authors:

Petit, Yves

Sanner, Caroline

Larcheveque, Marc

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Article abstract of DOI:10.1055/s-1988-27629

Both enantiomers of erythro methyl or ethyl 3-hydroxy-2-methylbutanoate were prepared by reaction of lithium dimethylcuprate with enantiomerically pure cis-2,3-epoxybutanoic esters derived from L- or D-threonine.

Full text of DOI:10.1055/s-1988-27629

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