Synthesis of new C-19-functionalized cholesterols

Article abstract of DOI:10.1016/0039-128X(94)90108-2

A series of new derivatives of cholesterol bearing polar functional groups on carbon-19 were synthesized, including 19-oximino-, 19-amino-, 19- (methylimino)-, 19-(methylamino)-, 19-mercapto-, and 19-(methylthio) cholesterol, and 3β-hydroxycholest-5-en-19-oic acid, as well as an unusual cyclosterol, 5,19-cyclocholest-6-en-3β-ol.