Tetrahedron Asymmetry p. 2185 - 2188 (1996)
Update date:2022-08-16
Topics:
Morris, K. Gail
Smith, Mark E.B.
Turner, Nicholas J.
Lilly, Malcolm D.
Mitra, Robin K.
Woodley, John M.
A practical procedure is reported for the use of the enzyme transketolase, from Escherichia coli, for asymmetric carbon-carbon bond synthesis. The reactions with the biocatalyst are conveniently carried out, on a gram scale, in unbuffered aqueous media by employing a pH autotitrator. An improved large scale synthesis of hydroxypyruvate is also reported.
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