Cross-coupling of Grignard reagents with alkyl halides or tosylates by the use of nickel or palladium containing perovskite

Article abstract of DOI:10.1016/j.tetlet.2010.12.011

Nickel and palladium-containing perovskites, LaFe_0.8Ni _0.2O₃ (LFNO) and LaFe_0.95Pd _0.05O₃ (LFPO), could be employed as effective catalyst sources for the cross-coupling of nonactivated alkyl halides and tosylates with Grignard reagents in the presence of conjugated dienes. The reaction proceeded efficiently at room temperature or below using only ca. 1 mol % of catalysts with respect to Ni or Pd and the perovskites were reused without considerable loss of activity.