REDUCTION OF ACID CHLORIDES WITH SODIUM BOROHYDRIDE IN N,N-DIMETHYLFORMAMIDE: NATURE OF THE REACTION INTERMEDIATE AND A METHOD FOR ITS CONVERSION TO THE CORRESPONDING ALDEHYDE WITH MINIMAL ALCOHOL FORMATION

DOI: 10.1016/0040-4039(81)80027-5

Source and publish data:

Tetrahedron Letters p. 11 - 14 (1981)

Update date:2022-08-16

Topics:

Authors:

Babler, James H.

Invergo, Benedict J.

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Article abstract of DOI:10.1016/0040-4039(81)80027-5

By use of sodium borohydride under the proper reaction conditions, direct conversion of both aliphatic and aromatic acid chlorides to the corresponding aldehyde can be achieved in 80-95percent yield.

Full text of DOI:10.1016/0040-4039(81)80027-5

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