Microbial synthesis of (+)-(3R)-ethyl 3-hydroxy-3-(3,4-dimethoxyphenyl)propionate

Article abstract of DOI:10.1016/0957-4166(96)00112-7

From the microbiological reduction of ethyl 3-oxo-3-(3,4-dimethoxyphenyl)-propionate, (+)-(3R)-ethyl 3-hydroxy-3-(3,4-dimethoxyphenyl)propionate was prepared on a quantitative scale. The absolute configuration was assigned by X-ray structural determination of the crystallized camphanate derivative.