Chiral ligand control in enantioselective reduction of ketones by SmI2 for ketyl radical addition to olefins

Article abstract of DOI:10.1016/S0040-4039(98)00799-0

Samarium(II) diiodide-mediated reductive coupling of ketones with α,β- unsaturated esters is shown to afford enantioselectively γ-butyrolactones by the addition of 2,2'-bis(diphenylphosphinyl)-1,1'-binaphthyl (BINAPO) as a chiral ligand.