Nazarov cyclization of an indolyl vinyl ketone promoted by acetyl chloride and sodium iodide: Formal synthesis of Bruceolline e

Article abstract of DOI:10.3987/COM-18-13866

An acetyl chloride/NaI-mediated Nazarov-type cyclization of an indolyl vinyl ketone was developed to give a cyclopenta[b]indole in high yield. An acyl Finkelstein reaction is a key feature for this unprecedented Nazarov-type cyclization.

Full text of DOI:10.3987/COM-18-13866

NAZAROV CYCLIZATION OF AN INDOLYL VINYL
KETONE PROMOTED BY ACETYL CHLORIDE AND
SODIUM IODIDE: FORMAL SYNTHESIS OF
BRUCEOLLINE E
Supporting Information
Takumi Abe*
Faculty of Pharmaceutical Sciences, Health Sciences University of Hokkaido,
Ishikari-tobetsu, Hokkaido 0610293, Japan
E-mail: abe-t@hoku-iryo-u.ac.jp
Contents
1. Copies of 1H, 13C-NMR spectra ---------------------------------------------------------------------------------------------------- 2–37
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