Crystallographic signatures of N6-methoxyadenine imino tautomer-silver complexes

Article abstract of DOI:10.1021/cg300231r

Detailed crystallographic analysis of four silver complexes of N9-benzyl-N⁶-methoxyadenine, 1, on the basis of three different counteranions and silver ion stoichiometry, is discussed in this article. 1 is a rare tautomer of adenine, which exhibits promutagenic behavior as it partly mimics hydrogen bond donor and acceptor properties of guanine and mispairs with cytosine. Complexes 2 and 4 exhibit discrete Ag₂L₂ dimer, while complex 3 shows two AgL₂ units in addition to a Ag ₂L₂ dimer, all in a head-to tail fashion. Complex 5, on the other hand, shows four AgL₂ units coordinated in a head-to-head fashion affording a three-dimensional lattice stabilized by CH??? F interactions. Various noncovalent interactions such as hydrogen bonding, CH-π interactions, argentophilic interactions, and Ag-π interactions stabilize these complexes.