Conformationally restricted peptides: Solution conformation of tetra and hepta peptides containing α,β-dehydrophenylalanine residues in alternate positions

Article abstract of DOI:10.1016/S0040-4020(01)80805-X

Two model peptides containing dehydrophenylalanine, a tetrapeptide 1 (Ac-Δ(Z)Phe-Pro-Δ(Z)Phe-Ala-OMe) and a heptapeptide 2 (Boc-Gly-Δ(Z)Phe-Val-Δ(Z)Phe-Ala-Δ(Z)Phe-Leu-OMe) have been synthesised and their solution conformations investigated by NMR and cir