Journal of the Chemical Society. Perkin transactions I p. 2603 - 2604 (1991)
Update date:2022-08-25
Topics:
Saville-Stones, Elizabeth A.
Lindell, Stephen D.
Jennings, Neil S.
Head, John C.
Ford, Mark J.
Cyclopentenyl allylic acetates have been prepared in diastereoisomerically enriched form by modification of the Prins reaction.Palladium(0) catalysed coupling between these allylic acetates and a heteroaromatic base provides a highly convergent and direct route for synthesising carbocyclic 2',3'-didehydro-2',3'-dideoxy nucleosides.The method is exemplified by the coupling reaction with adenine which yields (+/-)-2',3'-didehydro-2',3'-dideoxyaristeromycin 5'-O-acetate 22 in 50percent yield.This has been converted in two steps into (+/-)-aristeromycin triacetate 5.
View MoreContact:+86-531-58668191 58668193 58668196 58661173
Address:No 55,Beixiaoxinzhuang West Street,Jinan City, Shandong Province
website:https://en.yan-xi.com/
Contact:+86 17531190177--
Address:Zhang zhe, guangzong county, xingtai city, hebei province
Changzhou Screw International Trading Co., Ltd.
Contact:13906149256,18001495888
Address:Jiangsu，Jintanqu
ANHUI CHEM-BRIGHT BIOENGINEERING CO.,LTD
Contact:86-561-4080321
Address:No.8 Lieshan Industrial Zone of Huaibei
Contact:+86-29-88710656
Address:South Tai bai Road, High Tech Development Zone, Xi'an China
Doi:10.1039/jr9550002557
(1955)Doi:10.1002/open.202000239
(2020)Doi:10.1246/bcsj.50.1863
(1977)Doi:10.1021/acs.organomet.7b00807
(2018)Doi:10.1007/BF00978465
(1989)Doi:10.1039/d0ob02527e
(2021)
