Rationally designed organocatalyst for direct asymmetric aldol reaction in the presence of water

DOI: 10.1016/j.tetlet.2007.04.037

Source and publish data:

Tetrahedron Letters p. 4281 - 4285 (2007)

Update date:2022-08-10

Topics:

Authors:

Wang, Chao

Jiang, Yi

Zhang, Xiao-xia

Huang, Yi

Li, Bo-gang

Zhang, Guo-lin

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Article abstract of DOI:10.1016/j.tetlet.2007.04.037

A rationally designed organocatalyst for direct asymmetric aldol reaction in the presence of water has been developed. High yield (up to 99%), diastereoselectivity (up to 99:1) and enantioselectivity (up to 97%) were obtained under optimal conditions.

Full text of DOI:10.1016/j.tetlet.2007.04.037

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