Design, synthesis, and testing of potential antisickling agents. 10. (2,2-Dimethylchroman-6-yl)alkanoic acids

DOI: 10.1021/jm00394a007

Source and publish data:

Journal of Medicinal Chemistry p. 1973 - 1977 (1987)

Update date:2022-08-11

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Authors:

Fatope Fatope

Abraham Abraham

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Article abstract of DOI:10.1021/jm00394a007

Five (2,2-dimethylchroman-6-yl)alkanoic acids were synthesized and tested for antigelling activities. It was envisioned that these agents might bind via hydrophobic bonding to nonpolar sites of the 'donor-acceptor' regions of hemoglobin S. Several (2,2-di

Full text of DOI:10.1021/jm00394a007

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