Enantioselective Synthesis of 2-Isoxazolines via Asymmetric 1,3-Dipolar Cycloaddition of Nitrile Oxide to Achiral Allyl Alcohol

DOI: 10.1246/cl.1993.1847

Source and publish data:

Chemistry Letters p. 1847 - 1850 (1993)

Update date:2022-08-10

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Authors:

Ukaji, Yutaka

Sada, Kazunori

Inomata, Katsuhiko

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Article abstract of DOI:10.1246/cl.1993.1847

The asymmetric 1,3-dipolar cycloaddition of a nitrile oxide to an achiral allyl alcohol was achieved by the use of (R,R)-diisopropyl tartrate as a chiral auxiliary.Treatment of the allyl alcohol with diethylzinc and the tartrate, followed by the addition

Full text of DOI:10.1246/cl.1993.1847

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