Indium-Mediated Coupling of α-(Bromomethyl)acrylic Acid with Carbonyl Compounds in Aqueous Media. Concise Syntheses of (+)-3-Deoxy-D-glycero-D-galacto-nonulosonic Acid and N-Acetylneuraminic Acid

DOI: 10.1021/jo00118a044

Source and publish data:

Journal of Organic Chemistry p. 4228 - 4232 (1995)

Update date:2022-08-11

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Authors:

Chan, Tak-Hang

Lee, Ming-Chao

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Article abstract of DOI:10.1021/jo00118a044

Indium mediates the coupling of α-(bromomethyl)acrylic acid with carbonyl compounds in aqueous media to give the corresponding γ-hydroxy-α-methylene carboxylic acids.The reaction has been applied to the syntheses of (+)-3-deoxy-D-glycero-D-galacto-nonulos

Full text of DOI:10.1021/jo00118a044

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