Use of β-Methylphenylalanine (βMeF) Residues To Probe the Nature of the Interaction of Substance P with Its Receptor: Effects of βMeF-Containing Substance P Analogs on Rabbit Iris Smooth Muscle Contraction

DOI: 10.1021/jm00013a024

Source and publish data:

Journal of Medicinal Chemistry p. 2478 - 2482 (1995)

Update date:2022-08-11

Topics:

Authors:

Birney, David M.

Cole, Derek C.

Crosson, Craig E.

Kahl, Brenda F.

Neff, Bart W.

et al. et al.

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Article abstract of DOI:10.1021/jm00013a024

The effects of substituting (2S,3S)-β-methylphenylalanine (S-βMeF) or (2S,3R)-β-methylphenylalanine (R-βMeF) for the Phe⁷ and/or Phe⁸ residues of the tachykinin substance P (SP, RPKPQQFFGLM-NH2) upon the ability of SP to stimulate co

Full text of DOI:10.1021/jm00013a024

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