Tetrahedron Letters p. 6993 - 6996 (1998)
Update date:2022-08-28
Topics:
Kim, Sang Woong
Bauer, Shawn M.
Armstrong, Robert W.
A 96 member library of acylated dipeptides based on a known anticonvulsant was synthesized utilizing an Ugi four component condensation followed by derivitization through nucleophilic displacement of a Weinreb type amide. The library afforded compounds in reasonable yield and high purity after cleavage from solid support.
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