Synthesis of ketones with alkyl phosphonates and nitriles as acyl cation equivalent: Application of dephosphonylation reaction of β-functionalized phosphonate with hydride

Article abstract of DOI:10.1080/00397919708005633

The preparation of several α-substituted ketones is performed in a one-pot procedure with alkyl phosphonates and aromatic nitriles by subsequent treatment of LiAlH₄. A new method for nitriles used as an acyl cation equivalent is described.

Full text of DOI:10.1080/00397919708005633

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Synthetic Communications: An
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Organic Chemistry
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Synthesis of Ketones with
Alkyl Phosphonates and
Nitriles as Acyl Cation
Equivalent: Application of
Dephosphonylation Reaction of
β-Functionalized Phosphonate
with Hydride
Won Bum Jang a , Won Suk Shin a , Jong Eun Hong a
Shi Yong Lee a & Dong Young Oh a
a Department of Chemistry , Korea Advanced
,
Institute of Science and Technology , 373-1, Kusung-
Dong, Yusung-Gu, Taejon, 305-701, Korea E-mail:
Published online: 22 Aug 2006.
To cite this article: Won Bum Jang , Won Suk Shin , Jong Eun Hong , Shi Yong
Lee & Dong Young Oh (1997) Synthesis of Ketones with Alkyl Phosphonates and
Nitriles as Acyl Cation Equivalent: Application of Dephosphonylation Reaction
of β-Functionalized Phosphonate with Hydride, Synthetic Communications: An
International Journal for Rapid Communication of Synthetic Organic Chemistry, 27:19,
3333-3339, DOI: 10.1080/00397919708005633
To link to this article: http://dx.doi.org/10.1080/00397919708005633
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