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Scheme 6 Plausible reaction pathway.
1,7-diynes, leading to a wide range of functionalized b-gem-
dihalovinyl carbonyls in moderate to excellent yields. The
photocatalysis enjoys the complete control of regiochemistry
and good compatibility with a wide variety of easily available
1,7-diynes and alkyl halides such as BrCCl3 and CBr4, thus
opening a new avenue for photocatalytic functionalization of
diynes. The late-stage application of b-gem-dihalovinyl carbonyls
demonstrates their high and unique reactivity profiles and
highlights the versatility of their derivatization. Further investi-
gations of its mechanism and applications of photoredox
catalysis are underway in our laboratory.
We are grateful for financial support from the NSFC (No.
21871112, and 21971090), the Graduate Education Innovation
Project of Jiangsu Province (No. KYCX20_2250) and the Top-
Notch Academic Programs Project of Jiangsu Higher Education
Institution (TAPP).
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Conflicts of interest
There are no conflicts to declare.
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