Preparation and Study of Dinuclear Zinc(II) Complex for the Efficient Hydrolysis of the Phosphodiester Linkage in a Diribonucleotide

DOI: 10.1039/c39950001793

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 1793 - 1794 (1995)

Update date:2022-08-22

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Authors:

Yashiro, Morio

Ishikubo, Akira

Komiyama, Makoto

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Article abstract of DOI:10.1039/c39950001793

A dinuclear zinc(II) complex with N,N,N',N'-tetrakis<(2-pyridyl)methyl>-2-hydroxy-1,3-diaminopropane efficiently hydrolyses ApA at pH 7 and 50 deg C; the complex can thus be regarded as a good artificial ribonuclease which effectively mimics enzyme active sites.

Full text of DOI:10.1039/c39950001793

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