Fused Pyridine Derivatives from the Wittig Reaction of some Fluorinated Amides

Article abstract of DOI:10.1016/0040-4020(95)00605-8

Compound 2 reacted with phosphorane 3 (R = Et) giving the quinoline derivative 5 whereas thiophenes 7 and 9 gave enamines 8 and 10 respectively with the appropriate phosphorane 3 (R = Me or Et).Pyridine derivative 11 yielded only ethyl 2-aminonicotinate with phosphorane 3 (R = Et).Compounds 8 and 10 gave the fused pyridine derivatives 14 and 15 respectively.