Journal of Medicinal Chemistry p. 488 - 495 (1995)
Update date:2022-08-28
Topics:
Farquhar
Chen
Khan
5'-[4-(Pivatoyloxy)-1,3,2-dioxaphosphorinan-2-yl]-2'-deoxy-5- fluorouridine (1c) was designed as a potential membrane-permeable prodrug of 2'-deoxy-5-fluorouridine 5'-monophosphate (FdUMP), a putative active metabolite of the antitumor drug 5-fluorouracil
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