Ozonolysis of alkenes and study of reactions of polyfunctional compounds: LXVI. Ozonolysis and hydrogenation of diacetonides of 24,25- and 25,26-anhydro-20-hydroxyecdysones. Synthesis of ponasterone A

Article abstract of DOI:10.1023/A:1016547122573

Ozonolysis of 2,3:20,22-diacetonides of 24.25-and 25,26-anhydro-20-hydroxyecdysones afforded the corresponding ω-carbonyl derivatives. The hydrogenation of the mentioned dehydration products of 20-hydroxyecdysone acetonide yielded diacetonide of ponasterone A that provided ponasterone A and its 29,22-acetonide at hydrolysis.