Tetrahedron Asymmetry p. 1543 - 1546 (1992)
Update date:2022-08-11
Topics:
Cohen
Parratt
Turner
An immobilised whole cell catalyst SP361 has been shown to hydrolyse a range of 2-alkyl arylacetonitriles 1a-3a and amides 2b, 3b with good to excellent enantioselectivity. The absolute configuration of the derived amides and/or carboxylic acids shows remarkable changes according to the structure of the nitrile substrate.
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