1,1,3,3-Tetraethyl-1,3-disilaisoindolines; Chromatographically Stable Silicon-Based Protection for Primary Amines

Article abstract of DOI:10.1016/0040-4039(95)00462-L

The title compounds 4 have potential as protected derivatives of primary aliphatic amines.They are more stable to acid than the corresponding Stabase and Benzostabase derivatives 2 and 3, and are stable to flash chromatography on silica gel using all but the least polar solvent systems.