
Journal of the Chemical Society. Perkin transactions I p. 2974 - 2977 (1981)
Update date:2022-08-10
Topics:
Albert, Adrien
8-Trifluoromethylpurine (1a) was converted by catalytic hydrogenation entirely to the 1,6-dihydro-derivative (3a), whereas 9-methyl-8-trifluoromethylpurine (1b) produced a 2:1 mixture of the 1,6- (3b) and 7,8- (5) dihydroderivatives.The new hydrogenated purines are characterised by unusual stability.Physical properties are discussed and compared with those of analogues from several other heterocyclic series.
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