(1S,2S,7R,8aS)- and (1S,2S,7S,8aS)-trihydroxyoctahydroindolizine: Two new glycosidase inhibitors by nitrone cycloaddition strategy

Article abstract of DOI:10.1016/0957-4166(96)00200-5

The two new epimeric (1S,2S,7R,8aS)- and (1S,2S,7S,8aS)-1,2,7- trihydroxyoctahydroindolizines 4 and 5 have been synthesized via methylenecyclopropane-nitrone cycloaddition-rearrangement methodology employing an enantiomerically pure L-tartaric acid derive