A mild method for the preparation of 1,3,4-oxadiazoles: Triflic anhydride promoted cyclization of diacylhydrazines

Article abstract of DOI:10.1080/00397910008087340

Diacylhydrazines undergo cyclization upon treatment with triflic anhydride and pyridine to form the corresponding 1,3,4-oxadiazoles in yields ranging from 70-95%.

Full text of DOI:10.1080/00397910008087340

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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A Mild Method for the
Preparation of 1,3,4-
Oxadiazoles: Triflic Anhydride
Promoted Cyclization of
Diacylhydrazines
a
a
Spiros Liras , Martin P. Allen & Barb E. Segelstein
a
a
Neurosciences Medicinal Chemistry Central
Research Division Pfizer Inc , Groton, CT, 06340
Published online: 04 Dec 2007.
To cite this article: Spiros Liras , Martin P. Allen & Barb E. Segelstein (2000) A
Mild Method for the Preparation of 1,3,4-Oxadiazoles: Triflic Anhydride Promoted
Cyclization of Diacylhydrazines, Synthetic Communications: An International Journal
for Rapid Communication of Synthetic Organic Chemistry, 30:3, 437-443, DOI:
10.1080/00397910008087340
To link to this article: http://dx.doi.org/10.1080/00397910008087340
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