A new synthesis of the aporphine alkaloids (±)-glaucine and (±)-nantenine. Application of [3C + 3C] annelation to the D-ring formation

DOI: 10.1248/cpb.41.481

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 481 - 483 (1993)

Update date:2022-08-23

Topics:

Authors:

Ozaki Ozaki

Kubo Kubo

Kim Kim

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.41.481

A [3C + 3C] annelation using 1,1-bis(ethylthio)-2-propanone was applied to a new synthesis of the aporphine alkaloids. Condensation of the ketone with the Mannich base gave two isomeric cyclohexenones, which were converted into the aporphine framework by aromatization. (±)-Glaucine and (±)-nantenine were prepared by employing this new aromatic synthesis.

Full text of DOI:10.1248/cpb.41.481

NII-Electronic Library Service

Products guided by the article

Product name:(+/-)-glaucine

Cas No:139341-79-0

R&D Labs maybe for 139341-79-0

Beijing Mashi Fine Chemical Co.,Ltd.

Contact:+86-10-61271592

Address:Room 506, Section B, Kaichi Mansion, Industrial Development
Xinjiang Fufeng Biotechnologies Co., Ltd.

Contact:+86-539-7287111

Address:GANQUANPU INDUSTRIAL PARK, ECONOMIC AND TECHNOLOGICAL DEVELOPMENT AREA (TOUTUNHE DISTRICT) OF URUMQI
jiangsu hualin chemical co.,ltd.

Contact:86-25-87787402

Address:jaingsu,china
Huangshan Honghui Pharm Technology Co., Ltd.(expird)

website:http://www.honghuichem.com

Contact:18855958372

Address:Qingshan Wan No.1,Nanyuan Kou,SheXian Huangshan City,Anhui Province
Tianjin Ji Ping Jia Chemical Co., Ltd.

Contact:18622448868

Address:tianjin

Relevant to this article

Doi:10.1016/0022-1902(73)80483-X
(1973)
Molecular engineering and synthesis of symmetric metal-free organic sensitizers with A-π-D-π-A architecture for DSSC applications: the effect of bridge unit

Doi:10.1007/s13738-019-01713-3
(2019)
Et₃B/Et₂AlCl/O₂-Mediated Radical Coupling Reaction between α-Alkoxyacyl Tellurides and 2-Hydroxybenzaldehyde Derivatives

Doi:10.1002/asia.202001090
(2020)
The Fe(II)-Fe(IV) and Fe(III)-Fe(V) manifolds in an expanded world of gif chemistry

Doi:10.1016/S0040-4039(00)78189-5
(1994)
Synthesis, biological evaluation and molecular docking study of hydrazone-containing pyridinium salts as cholinesterase inhibitors

Doi:10.1248/cpb.c16-00221
(2016)
Anti-Sulfonamide antibodies catalyse the hydrolysis of a heterocyclic amide

Doi:10.1039/cc9960001417
(1996)

Article Doi