Synthetic Communications p. 2253 - 2257 (2006)
Update date:2022-08-11
Topics:
Hermet, Jean-Paul
Caubert, Virginie
Langlois, Nicole
tert -Butyl 4-methyl-2-oxo-2,5-dihydro-1 H -pyrrole-1-carboxylate 4 was synthesized by a short two-step procedure: regioselective 1,3-dipolar diazomethane cycloaddition to N -Boc-pyrrolinone 2 and thermolysis of the adduct. The compound 4 could be converted in one step into pulchellalactam. Copyright Taylor & Francis Group, LLC.
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