Synthetic Communications p. 2857 - 2863 (2010)
Update date:2022-08-11
Topics:
Joshi, Jigar H.
Saiyed, Akeel S.
Bedekar, Ashutosh V.
An aqueous aza-Michael reaction is efficiently achieved with excellent conversions without any additives. The method works very well on a molar scale with selectively for aliphatic amines. An intermediate for spermine is also made by this green process.
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