Tetrahedron Letters p. 5867 - 5870 (1993)
Update date:2022-08-11
Topics:
Waldmann, Herbert
Schmidt, Gunther
Jansen, Martin
Geb, Jutta
The Pictet-Spengler cyclization of iminium salts generated in situ from N-(β-3-indolyl)ethyl substituted amino acid esters and differently substituted aldehydes proceeds with high stereoselectivity to deliver chiral tetrahydro-β-carbolines with diastereomer ratios up to 98.5:1.5.
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