Preparation of Novel Lipophilic GABA Analogues Containing Cyclopropane Rings via Cyclopropanation of N-Silylated Unsaturated Amines

DOI: 10.1002/prac.19953370112

Source and publish data:

Journal fur Praktische Chemie - Chemiker-Zeitung p. 55 - 59 (1995)

Update date:2022-08-17

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Authors:

Paulini, Klaus

Reissig, Hans-Ulrich

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Article abstract of DOI:10.1002/prac.19953370112

Novel lipophilic γ-amino acids 8 and 9 analogous to GABA containing cyclopropane rings are synthesized by Rh(II)-catalyzed reaction of diazo compounds 2 and 3 with N,N-bis(trimethylsilyl)allylamine (1) and subsequent hydrolysis.In addition, routes are des

Full text of DOI:10.1002/prac.19953370112

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