Bioorganic and Medicinal Chemistry Letters p. 2117 - 2122 (1998)
Update date:2022-08-11
Topics:
Massa, Mark A.
Patt, William C.
Ahn, Kyunghye
Sisneros, Andre M.
Herman, Sarah B.
Doherty, Annette
A series of bi-aryl pyridine carboxylic acids has been prepared and evaluated as inhibitors of ECE-1. The analogs were prepared by Pd catalyzed cross couplings of halogenated pyridines with heteroaryl organo -boranes, - tinate or -zincate derivatives.
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