Synthesis of (E)-2-(4,7-dichloroquinolin-2-yl)-3-dimethylamino-2-propene-1-al and its use as a synthetic intermediate

DOI: 10.1016/0040-4039(94)02248-A

Source and publish data:

Tetrahedron Letters p. 205 - 208 (1995)

Update date:2022-08-10

Topics:

Authors:

De, Dibyendu

Mague, Joel T.

Byers, Larry D.

Krogstad, Donald J.

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Article abstract of DOI:10.1016/0040-4039(94)02248-A

A novel synthesis is described for (E)-2-(4,7-dichloroquinolin-2-yl)-3-dimethylamino-2-propene-1-al (4), which reacts with nucleophiles to yield heterocycle-substituted 4,7-dichloroquinolines (5-7).

Full text of DOI:10.1016/0040-4039(94)02248-A

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